منابع مشابه
Regulation of Bone Metabolism
Bone is formed through the processes of endochondral and intramembranous ossification. In endochondral ossification primary mesenchymal cells differentiate to chondrocytes and then are progressively substituted by bone, while in intramembranous ossification mesenchymal stem cells (MSCs) differentiate directly into osteoblasts to form bone. The steps of osteogenic proliferation, differentiation,...
متن کاملregulation of bone metabolism
bone is formed through the processes of endochondral and intramembranous ossification. in endochondral ossification primary mesenchymal cells differentiate to chondrocytes and then are progressively substituted by bone, while in intramembranous ossification mesenchymal stem cells (mscs) differentiate directly into osteoblasts to form bone. the steps of osteogenic proliferation, differentiation,...
متن کاملRegulation of Lipid Metabolism and Beyond
One of the worldwide health issues is the increasing number of obese population. In 1975 it was less than 100 million but it reached 600 million in 2014 according to WHO report in 2015. More than one-third of adults and 17% of youth are obese in America [1, 2]. Obesity is one of the major risk factors for diverse human diseases and more and more research papers are coming to dissect the mechani...
متن کاملRole of hepatic STAT3 in the regulation of lipid metabolism.
Regulation of hepatic gene expression is largely responsible for the control of nutrient metabolism. We previously showed that the transcription factor STAT3 regulates glucose homeostasis by suppressing the expression of gluconeogenic genes in the liver. However, the role of STAT3 in the control of lipid metabolism has remained unknown. We have now investigated the effects of hepatic overexpres...
متن کاملRegulation of lipid metabolism by the AMP-activated protein kinase.
The AMP-activated protein kinase (AMPK) is the central component of a protein kinase cascade which plays an important role in the regulation of many different aspects of lipid metabolism [1,2]. AMPK is activated 50to 100-fold by phosphorylation by an upstream protein kinase, AMPK kinase (AMPKK) [3]. The key regulators of the AMPK cascade currently appear to be S’-AMP and ATP. AMP activates the ...
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ژورنال
عنوان ژورنال: Frontiers in Biology
سال: 2011
ISSN: 1674-7984
DOI: 10.1007/s11515-011-1159-x